Vice City Mambas is the main football team of Vice City in the GTA III era. BJ Smith and Jose Pimsoll used to play on the team. In a Grand Theft Auto Advance mission called Two-Hand Toss. On the orders of Asuka Kasen, protagonist Mike had to injure the quarterback of the Mambas to improve the chances of the Liberty City Cocks to win.
The Vice City Mambas is most likely to be based off of Miami's football team, the Miami Dolphins.